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Of the various genetic linkage and association studies, the one that seems to be a possible 'marker' for schizophrenia involves


A) eye-tracking.
B) dopamine sites.
C) unusual facial features.
D) blood type.

E) A) and B)
F) A) and C)

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The neuroleptic drugs introduced in the 1950s affect primarily the positive symptoms of schizophrenia, which include all of the following EXCEPT


A) hallucinations.
B) delusions.
C) social deficits.
D) agitation.

E) C) and D)
F) None of the above

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In which of the following situations would the risk of developing schizophrenia be the LOWEST for a child?


A) A child's schizophrenic parent has a non-schizophrenic identical twin.
B) A child's non-schizophrenic parent has a schizophrenic identical twin.
C) A child's schizophrenic parent has a non-schizophrenic fraternal twin.
D) A child's non-schizophrenic parent has a schizophrenic fraternal twin.

E) All of the above
F) B) and D)

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There are cross-cultural differences in the treatment of schizophrenia.For example, a schizophrenic patient in China might receive treatments including_____________ in addition to antipsychotic medication.


A) burning candles
B) burning joss sticks
C) both of these are correct
D) neither of these are correct

E) All of the above
F) A) and D)

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C

Which of the following statements contradicts the dopamine theory of schizophrenia?


A) Many people with schizophrenia are not helped by dopamine antagonists.
B) Olanzapine, one of the weakest dopamine antagonists, reduces schizophrenic symptoms in those patients who were not helped by stronger dopamine antagonists.
C) Both of these statements contradict the dopamine theory of schizophrenia.
D) Neither of these statements contradicts the dopamine theory of schizophrenia.

E) B) and C)
F) A) and C)

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C

The negative schizophrenic symptom called anhedonia is defined as


A) an inability to initiate or persist in activities.
B) an inability to experience pleasure.
C) a lack of emotional response, blank facial expression.
D) a lack of speech content and/or slowed speech response.

E) None of the above
F) A) and D)

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Families with a high expressed emotion (EE) score view the symptoms of schizophrenia as


A) controllable.
B) uncontrollable.
C) inevitable.
D) inconvenient.

E) B) and C)
F) A) and B)

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If an individual is diagnosed as psychotic, it usually means that the person has


A) hallucinations.
B) delusions.
C) both of these.
D) neither of these.

E) B) and C)
F) A) and B)

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With regard to the family interactions among schizophrenic patients, the word 'schizophrenogenic' (no longer used) , was first proposed in the 1940s to describe


A) an abusive and alcoholic father whose child became schizophrenic.
B) an emotionally distant mother whose child became schizophrenic.
C) divorced parents who had several psychotic children.
D) a family in which relatives on both sides were psychotic.

E) A) and C)
F) A) and B)

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Assertive community treatment for schizophrenia utilises


A) medication management.
B) psychological treatment.
C) vocational treatment.
D) all of the above

E) All of the above
F) A) and B)

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Which of the following statistical data are NOT accurate regarding schizophrenia?


A) The lifetime prevalence rate is 3%.
B) Life expectancy is less than average due to suicides and accidents.
C) Men with schizophrenia have a poorer prognosis than women with schizophrenia.
D) More women than men develop schizophrenia later in life.

E) A) and C)
F) B) and C)

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The famous case of the Genain sisters, identical quadruplets all diagnosed with schizophrenia, points out that siblings raised in the same household may experience their environment very differently, a concept called a(n)


A) variable home structure.
B) unshared environment.
C) environmental phenomenon.
D) unique perceptive interpretation.

E) B) and D)
F) A) and B)

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Which of the following occurs when drugs are administered to schizophrenic patients?


A) Drugs that increase dopamine (agonists) cause an increase in schizophrenic behaviour.
B) Drugs that decrease dopamine (antagonists) decrease schizophrenic symptoms.
C) Both of these statements are accurate.
D) Neither of these statements is accurate.

E) C) and D)
F) A) and B)

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Which of the following is the most accurate definition of flat affect?


A) An inability to initiate and persist in activities.
B) The inability to experience pleasure.
C) A lack of emotional response, blank facial expression.
D) A lack of speech content and/or slowed speech response.

E) A) and C)
F) None of the above

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The positive symptoms of schizophrenia are most closely associated with _________ activity.


A) serotonin
B) dopamine
C) norepinephrine
D) acetylcholine

E) None of the above
F) A) and B)

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Which of the following is the best description of schizophrenia?


A) Schizophrenia is characterised by symptoms shared by everyone with the diagnosis.
B) Schizophrenia is characterised by multiple personalities.
C) Schizophrenia is characterised by behaviour and symptoms that are not necessarily common to everyone with the diagnosis.
D) The course of schizophrenia is always predictable.

E) A) and B)
F) A) and C)

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C

During the 1990s, a new class of antipsychotic medications became available to treat schizophrenic patients who were not helped by conventional antipsychotic medications or who had developed unpleasant side effects.These new antipsychotic medications include all of the following EXCEPT


A) Largactil (chlorpromazine)
B) Leponex (clozapine)
C) Risperdal (risperidone)
D) Zyprexa (olanzapine)

E) B) and C)
F) None of the above

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New research on schizophrenia suggests that


A) only D2 receptors are involved in schizophrenia.
B) D2 receptors may be involved whenD1 receptors are less active.
C) D2 receptors may be involved whenD1 receptors are more active.
D) dopamine is not actually involved in schizophrenia.

E) A) and D)
F) All of the above

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A treatment first used in the 1930s as a treatment for schizophrenia but now used primarily to treat severe depression is


A) electroconvulsive therapy (ECT) .
B) prefrontal lobotomy.
C) insulin coma therapy.
D) psychosurgery.

E) C) and D)
F) All of the above

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Which of the following has recently been linked to schizophrenia?


A) deficiency in the stimulation of prefrontal dopamine D1 receptors
B) excessive stimulation of striatal dopamine D2 receptors
C) alterations in prefrontal activity involving glutamate transmissions
D) all of the above

E) None of the above
F) B) and C)

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