Question 1

AMPA trafficking is regulated _______ and by _______.

Accepted Answer

The answer of AMPA trafficking is regulated _______ and by...

Question 2

The delivery of AMPA receptors produced by LTP induction involves both lateral diffusion and the exocytic processes.

Accepted Answer

A) True 
 B)False

Question 3

Which is/are shared by NMDA and AMPA receptors? (Select all that apply.)

Accepted Answer

A)   Neither bind to glutamate.
B)   Both have a magnesia binding site.
C)   Both require depolarizing in order to open the channel.
D)   Both are voltage gated.
E)   None of the above.F) A) and C)
G) A) and B)

Question 4

What is an excitatory synapse?

Accepted Answer

The answer of What is an excitatory synapse?...

Question 5

The opening of NMDA receptor channels require synaptic depolarization.

Accepted Answer

A) True 
 B)False  True

Question 6

You could block the expression of LTP by inhibiting _______ receptors.

Accepted Answer

The answer of You could block the expression of LTP...

Question 7

Glutamate receptors involved in LTP are found along the axon.

Accepted Answer

A) True 
 B)False

Question 8

AMPA receptors influx mainly Na+; NMDA receptors influx both Na+ and Ca2+.

Accepted Answer

A) True 
 B)False

Question 9

Stargazin is critical to the trapping of AMPA receptors in the PSD.

Accepted Answer

A) True 
 B)False

Question 10

Competitive antagonists, such as APV, can replace a ligand and cause conformational changes in the receptor.

Accepted Answer

A) True 
 B)False

Question 11

What are the two conditions that must be met for Ca2+ ions to flow into the neuron?

Accepted Answer

1) ligand binding (glutamate); 2) synaptic depolarization

Question 12

Which term(s)  applies/apply to glutamate? (Select all that apply.)

Accepted Answer

A)   Neurotransmitter
B)   First messenger
C)   Ligand
D)   Receptor
E)   None of the above.F) All of the above
G) A) and C)

Question 13

Phosphatases add phosphates to other proteins.

Accepted Answer

A) True 
 B)False

Question 14

Which statement(s)  about LTP is/are false? (Select all that apply.)

Accepted Answer

A)   NMDA and AMPA receptors are required for the induction of LTP.
B)   CNQX can inhibit induction, but not expression, of LTP.
C)   APV can inhibit induction, but not expression, of LTP.
D)   To express LTP, NMDA and AMPA channels are crucial.
E)   None of the aboveF) C) and E)
G) D) and E) B,D

Question 15

Glutamate is an excitatory neurotransmitter.

Accepted Answer

A) True 
 B)False

Question 16

What is APV, and what is its function?

Accepted Answer

The answer of What is APV, and what is its...

Question 17

Why would an increase in the population of AMPA receptors increase the fEPSP?

Accepted Answer

The answer of Why would an increase in the population...

Question 18

Why should inhibiting AMPA receptors prevent the expression of LTP?

Accepted Answer

The answer of Why should inhibiting AMPA receptors prevent the...

Question 19

The degradation of the actin cytoskeleton depends on spectrins degrading calpains.

Accepted Answer

A) True 
 B)False

Question 20

Why should inhibiting NMDA receptors prevent the degradation of the actin cytoskeleton?

Accepted Answer

The answer of Why should inhibiting NMDA receptors prevent the...

Exam 3: Generating Long-Term Potentiation

AMPA trafficking is regulated _______ and by _______.

Correct AnswerverifiedShow Answer

The delivery of AMPA receptors produced by LTP induction involves both lateral diffusion and the exocytic processes.

Correct AnswerverifiedShow Answer

Which is/are shared by NMDA and AMPA receptors? (Select all that apply.)

Correct AnswerverifiedShow Answer

What is an excitatory synapse?

Correct AnswerverifiedShow Answer

The opening of NMDA receptor channels require synaptic depolarization.

Correct AnswerverifiedTrue

You could block the expression of LTP by inhibiting _______ receptors.

Correct AnswerverifiedShow Answer

Glutamate receptors involved in LTP are found along the axon.

Correct AnswerverifiedShow Answer

AMPA receptors influx mainly Na+; NMDA receptors influx both Na+ and Ca2+.

Correct AnswerverifiedShow Answer

Stargazin is critical to the trapping of AMPA receptors in the PSD.

Correct AnswerverifiedShow Answer

Competitive antagonists, such as APV, can replace a ligand and cause conformational changes in the receptor.

Correct AnswerverifiedShow Answer

What are the two conditions that must be met for Ca2+ ions to flow into the neuron?

Correct Answerverified1) ligand binding (glutamate); 2) synaptic depolarization

Which term(s) applies/apply to glutamate? (Select all that apply.)

Correct AnswerverifiedShow Answer

Phosphatases add phosphates to other proteins.

Correct AnswerverifiedShow Answer

Which statement(s) about LTP is/are false? (Select all that apply.)

Correct AnswerverifiedB,D

Glutamate is an excitatory neurotransmitter.

Correct AnswerverifiedShow Answer

What is APV, and what is its function?

Correct AnswerverifiedShow Answer

Why would an increase in the population of AMPA receptors increase the fEPSP?

Correct AnswerverifiedShow Answer

Why should inhibiting AMPA receptors prevent the expression of LTP?

Correct AnswerverifiedShow Answer

The degradation of the actin cytoskeleton depends on spectrins degrading calpains.

Correct AnswerverifiedShow Answer

Why should inhibiting NMDA receptors prevent the degradation of the actin cytoskeleton?

Correct AnswerverifiedShow Answer

AMPA trafficking is regulated _ and by _.

Correct Answer
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True

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AMPA receptors influx mainly Na⁺; NMDA receptors influx both Na⁺ and Ca²⁺.

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What are the two conditions that must be met for Ca²⁺ ions to flow into the neuron?

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1) ligand binding (glutamate); 2) synaptic depolarization

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B,D

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