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 A receptor can directly open a channel and thereby exert a(n) ____ effect, or it can produce slower but longer ____ effect.


A) gated; metabotropic
B) ionotropic; gated
C) metabotropic; ionotropic
D) ionotropic; metabotropic

E) All of the above
F) A) and B)

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 Sherrington found that repeated stimuli within a brief time have a cumulative effect. He referred to this phenomenon as ____.


A) temporal summation
B) spatial summation
C) synaptic summation
D) saltatory summation

E) A) and B)
F) B) and D)

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 Neurons communicate with both electrical and chemical signals. Scientists have shown that chemical communication is the preferred form as it is faster.

A) True
B) False

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 Briefly compare the differences between ionotropic and metabotropic receptors. Include their mechanisms of action and how they explain the difference in the effects on the postsynaptic cell.

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Ionotropic receptors are ion channels th...

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 Transmission of information between neurons occurs in the same way as transmission along an axon.

A) True
B) False

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 How are neurotransmitters removed from the synapse?

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Some neurotransmitters like acetylcholin...

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 Describe the main chemical events at a synapse.

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Understanding the chemical events at a s...

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 An IPSP represents ____.


A) the location where a dendrite branches
B) a gap in a myelin sheath
C) a subthreshold depolarization
D) a temporary hyperpolarization

E) A) and D)
F) None of the above

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 Receptor molecules for neurotransmitters that exert metabotropic effects are proteins that bind to ____ outside the membrane, and attach to ____ inside the membrane.


A) calcium; potassium
B) neurotransmitters; nicotine
C) neurotransmitters; G-proteins
D) adenosine; nitric oxide

E) A) and D)
F) All of the above

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 Most of the brain's excitatory ionotropic synapses use the neurotransmitter glutamate.

A) True
B) False

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 Although slower than an action potential, synaptic transmission is still relatively fast because ____.


A) the synaptic cleft is very narrow
B) sodium ions are transported quickly
C) neurotransmitters diffuse faster than electricity
D) EPSPs travel faster than IPSPs

E) B) and C)
F) A) and D)

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 Most of the known neurotransmitters are synthesized from amino acids.

A) True
B) False

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 At synapses, the cell that receives the message is called the presynaptic neuron.

A) True
B) False

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 What do temporal summation and spatial summation have in common?


A) Both involve the activity of only two neurons.
B) Both require a response from the brain.
C) Both depend on a combination of visual and auditory stimuli.
D) Both enable a reflex to occur in response to weak stimuli.

E) A) and B)
F) B) and C)

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 Which one of Sherrington's inferences about the synapse was wrong?


A) Transmission at a synapse is slower than transmission of impulses along an axon.
B) Transmission at the synapse is primarily an electrical process.
C) Synapses can be either excitatory or inhibitory.
D) Synapses make spatial summation and temporal summation possible.

E) A) and C)
F) B) and C)

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 Insulin increases the entry of tryptophan into the brain by ____.


A) weakening the blood-brain barrier
B) converting tryptophan into a compound that more easily enters the brain
C) increasing metabolic activity only in those areas of the brain that use tryptophan
D) causing certain competing amino acids to enter other cells, outside the brain

E) A) and B)
F) A) and C)

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 Which process indicates spatial summation?


A) Present two or more weak stimuli at the same time.
B) Start action potentials at both ends of one axon at the same time.
C) Do not allow a flexor muscle to relax before stimulating it again.
D) Present a rapid sequence of weak stimuli.

E) All of the above
F) B) and D)

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 Generally speaking, a neuron will release a greater number of neurotransmitters than what it will respond to with its own receptors.

A) True
B) False

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 Why is the speed of conduction through a reflex arc slower than the speed of conduction of an action potential along an axon?


A) Transmission between neurons at synapses is slower than along axons.
B) The longer an axon, the slower its velocity.
C) Interneurons have thicker axons than other neurons.
D) There are greater amounts of myelin involved in the reflex arc.

E) B) and D)
F) B) and C)

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 An action potential causes the release of neurotransmitters by ____.


A) blocking potassium pores in the membrane
B) opening chloride pores in the membrane
C) blocking iron pores in the membrane
D) opening calcium pores in the membrane

E) All of the above
F) A) and D)

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